Thomas E Smithgall Selected Research

Protein Kinases (Protein Kinase)

11/2006

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases.

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Thomas E Smithgall Research Topics

Disease

18	Neoplasms (Cancer) 12/2023 - 04/2002
12	Acquired Immunodeficiency Syndrome (AIDS) 10/2020 - 11/2004
6	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 03/2013 - 11/2002
5	Infections 09/2015 - 12/2004
5	Carcinogenesis 01/2012 - 11/2002
5	Squamous Cell Carcinoma of Head and Neck 05/2006 - 04/2002
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2022 - 01/2017
3	Myeloid Leukemia (Leukemia, Myelocytic) 11/2022 - 11/2002
3	Inflammation (Inflammations) 01/2022 - 03/2010
3	Colorectal Neoplasms (Colorectal Cancer) 03/2010 - 03/2006
2	Hematologic Neoplasms (Hematological Malignancy) 10/2018 - 01/2018
2	Leukemia 01/2016 - 02/2009
2	Virus Diseases (Viral Diseases) 01/2015 - 10/2011
2	Head and Neck Neoplasms (Head and Neck Cancer) 09/2004 - 04/2002
1	Merkel Cell Carcinoma 12/2023
1	Communicable Diseases (Infectious Diseases) 07/2021
1	Chronic Disease (Chronic Diseases) 10/2020
1	Neoplasm Metastasis (Metastasis) 08/2015
1	Rubella (German Measles) 01/2015
1	Chickenpox 01/2015
1	Herpes Zoster 01/2015
1	Cognitive Dysfunction 12/2013
1	Colonic Neoplasms (Colon Cancer) 03/2010
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2009
1	Leukopenia 04/2004
1	Anemia 04/2004

Drug/Important Bio-Agent (IBA)

20	Proteins (Proteins, Gene)FDA Link 12/2023 - 08/2003
13	Phosphotransferases (Kinase)IBA 01/2020 - 11/2002
10	src-Family KinasesIBA 11/2022 - 11/2002
10	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2020 - 11/2002
3	ErbB Receptors (EGF Receptor)IBA 05/2006 - 04/2002
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 07/2021 - 01/2017
2	Tyrosine (L-Tyrosine)FDA Link 10/2018 - 03/2006
2	bcr-abl Fusion ProteinsIBA 03/2013 - 11/2002
2	Imatinib Mesylate (Gleevec)FDA Link 02/2013 - 07/2010
2	Gastrin-Releasing PeptideIBA 05/2006 - 09/2004
2	nef Gene Products (nef Gene Product)IBA 12/2004 - 11/2004
2	Protein Isoforms (Isoforms)IBA 10/2003 - 04/2002
1	Tumor Viral Antigens (Large T Antigen)IBA 12/2023
1	Adenosine Triphosphate (ATP)IBA 11/2022
1	Codon (Codons)IBA 01/2020
1	Choline KinaseIBA 11/2019
1	EndoribonucleasesIBA 09/2015
1	Interleukin-17 (Interleukin 17)IBA 09/2015
1	Focal Adhesion Protein-Tyrosine KinasesIBA 08/2015
1	Conditioned Culture MediaIBA 01/2015
1	LuciferasesIBA 01/2015
1	MicroRNAs (MicroRNA)IBA 01/2015
1	Myristic Acid (Tetradecanoic Acid)IBA 03/2013
1	DNA (Deoxyribonucleic Acid)IBA 03/2010
1	Transcription Factors (Transcription Factor)IBA 03/2010
1	Decitabine FDA Link 03/2010
1	MethyltransferasesIBA 03/2010
1	NF-kappa B (NF-kB)IBA 03/2010
1	Oncogene Proteins (Oncogene Protein)IBA 06/2009
1	Small Interfering RNA (siRNA)IBA 01/2009
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2007
1	Protein Kinases (Protein Kinase)IBA 11/2006
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 05/2006
1	Anti-HIV Agents (AIDS Drugs)IBA 11/2004
1	AmphiregulinIBA 09/2004
1	Transforming Growth Factor alpha (TGF-alpha)IBA 09/2004
1	LigandsIBA 09/2004
1	Epidermal Growth Factor (EGF)IBA 09/2004
1	Matrix Metalloproteinase InhibitorsIBA 09/2004
1	marimastatIBA 09/2004
1	Bombesin Receptors (Bombesin Receptor)IBA 09/2004
1	ArsenicIBA 04/2004
1	Antisense OligonucleotidesIBA 10/2003
1	CytokinesIBA 11/2002
1	pyrimidineIBA 11/2002
1	STAT5 Transcription FactorIBA 11/2002

Therapy/Procedure

6	Therapeutics 10/2020 - 07/2007
1	Transcutaneous Electric Nerve Stimulation (TENS) 01/2022